Effectiveness of Muscimol‐containing Microparticles against Pilocarpine‐induced Focal Seizures
نویسندگان
چکیده
منابع مشابه
Auditory manifestations during focal seizures.
Interictal and particularly ictal surface and invasive recordings allow, in most of cases, the precise localization of the cortical area responsible of ictal discharges. During surface Video-EEG the localization could be a little complicated, considering the presence of artefacts, but the occurrence of a low voltage fast activity or a fl attening, permits, coupling with the onset of clinical sy...
متن کاملAlterations of the electroencephalogram sub-bands amplitude during focal seizures in the pilocarpine model of epilepsy
Introduction: Temporal lobe epilepsy (TLE) is the most common and drug resistant epilepsy in adults. Due to behavioral, morphologic and electrographic similarities, pilocarpine model of epilepsy best resembles TLE. This study was aimed at determination of the changes in electroencephalogram (EEG) sub-bands amplitude during focal seizures in the pilocarpine model of epilepsy. Analysis of thes...
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Focal epilepsy is commonly pharmacoresistant, and resective surgery is often contraindicated by proximity to eloquent cortex. Many patients have no effective treatment options. Gene therapy allows cell-type specific inhibition of neuronal excitability, but on-demand seizure suppression has only been achieved with optogenetics, which requires invasive light delivery. Here we test a combined chem...
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INTRODUCTION Seizures are most commonly associated with positive phenomena such as tonic, clonic or myoclonic movements, automatisms, paresthesias and hallucinations. Negative phenomena, however, are not an uncommon manifestation of seizure activity. Examples of negative seizure phenomena include speech arrest, aphasia, amaurosis, amnesia, numbness, deafness, neglect and atonic seizures. Less c...
متن کاملFocal seizures due to chronic localized encephalitis.
OCCASIONAL SPECIMENS of scarred, atrophic brain removed for the relief of focal cerebral seizures at the Montreal Neurological Institute have shown striking perivascular collections of round cells, particularly in less severely damaged areas of these specimens. In the past this perivascular cuffing has been attributed to the effect on the brain of recurring seizures, with recognition, however, ...
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ژورنال
عنوان ژورنال: Epilepsia
سال: 2002
ISSN: 0013-9580,1528-1167
DOI: 10.1046/j.1528-1157.2002.11202.x